Synthesized peptide derived from human R-Ras (Phospho-Tyr66)

This antibody detects endogenous levels of R-Ras (Phospho-Tyr66) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):DSyTK

RRAS

R-Ras (Phospho-Tyr66)

Ras-related protein R-Ras ;
p23 ;

The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis , vascular homeostasis and regeneration , cell adhesion , and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq , Jul 2015] ,

Function:Regulates the organization of the actin cytoskeleton. ,similarity:Belongs to the small GTPase superfamily. Ras family. ,subcellular location:Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS) . ,subunit:Interacts with PLCE1. ,

Cell membrane ; Lipid-anchor ; Cytoplasmic side . Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS) .

>>MAPK signaling pathway ;
>>Ras signaling pathway ;
>>Rap1 signaling pathway ;
>>cAMP signaling pathway ;
>>Phospholipase D signaling pathway ;
>>Mitophagy - animal ;
>>Autophagy - animal ;
>>Cellular senescence ;
>>Axon guidance ;
>>Apelin signaling pathway ;
>>C-type lectin receptor signaling pathway ;
>>Regulation of actin cytoskeleton ;
>>Salmonella infection ;
>>Proteoglycans in cancer