LDHA (Phospho Tyr10) Rabbit pAb
-YP1385
主要信息
Target
LDHA Phospho Tyr10
Host Species
Rabbit
Reactivity
Human
Applications
WB, IHC, ELISA
MW
36kD (Observed)
Conjugate/Modification
phosphate
货号: YP1385
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Human Mouse Rat LDHA (phospho-Tyr10)
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
36kD
修饰
phosphate
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized phosho peptide around human LDHA (Tyr10)
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特异性:
This antibody detects endogenous levels of Human Mouse Rat LDHA (phospho-Tyr10)
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基因名称:
LDHA PIG19
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蛋白名称:
LDHA (Tyr10)
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别名:
L-lactate dehydrogenase A chain ;
LDH-A ;
Cell proliferation-inducing gene 19 protein ;
LDH muscle subunit ;
LDH-M ;
Renal carcinoma antigen NY-REN-59 ;
LDH-A ;
Cell proliferation-inducing gene 19 protein ;
LDH muscle subunit ;
LDH-M ;
Renal carcinoma antigen NY-REN-59 ;
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背景:
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq , Sep 2008] ,
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功能:
Catalytic activity: (S) -lactate + NAD (+) = pyruvate + NADH. ,Caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. ,Disease:Defects in LDHA are a cause of exertional myoglobinuria. ,online information:Lactate dehydrogenase entry ,pathway:Fermentation; pyruvate fermentation to lactate; (S) -lactate from pyruvate: step 1/1. ,similarity:Belongs to the LDH/MDH superfamily. ,similarity:Belongs to the LDH/MDH superfamily. LDH family. ,subunit:Homotetramer. ,
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细胞定位:
Cytoplasm.
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研究领域:
>>Glycolysis / Gluconeogenesis ;
>>Cysteine and methionine metabolism ;
>>Pyruvate metabolism ;
>>Propanoate metabolism ;
>>Metabolic pathways ;
>>HIF-1 signaling pathway ;
>>Glucagon signaling pathway ;
>>Central carbon metabolism in cancer
>>Cysteine and methionine metabolism ;
>>Pyruvate metabolism ;
>>Propanoate metabolism ;
>>Metabolic pathways ;
>>HIF-1 signaling pathway ;
>>Glucagon signaling pathway ;
>>Central carbon metabolism in cancer
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信号通路
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货号: YP1385
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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