PDE3A (Phospho Ser312) Rabbit pAb
-YP1737
主要信息
Target
PDE3A Phospho Ser312
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
126kD (Calculated)
Conjugate/Modification
Phospho
货号: YP1737
规格
价格
货期
数量
200μL
￥4,680.00
两周
0
100μL
￥2,800.00
两周
0
50μL
￥1,500.00
两周
0
加入购物车
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of PDE3A (Phospho-Ser312) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RTsLP
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
126kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
抗原&靶点信息
免疫原:
Synthesized peptide derived from human PDE3A (Phospho-Ser312)
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特异性:
This antibody detects endogenous levels of PDE3A (Phospho-Ser312) at Human, Mouse,Rat.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RTsLP
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基因名称:
PDE3A
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蛋白名称:
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
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别名:
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A ;
Cyclic GMP-inhibited phosphodiesterase A ;
CGI-PDE A ;
cGI-PDE ;
cGMP-inhibited cAMP phosphodiesterase ;
Cyclic GMP-inhibited phosphodiesterase A ;
CGI-PDE A ;
cGI-PDE ;
cGMP-inhibited cAMP phosphodiesterase ;
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背景:
This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011],
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功能:
Catalytic activity:Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate.,enzyme regulation:Inhibited by cGMP.,Function:Hydrolyzes both cyclic AMP (cAMP) and cyclic GMP (cGMP).,online information:PDE3 entry,similarity:Belongs to the cyclic nucleotide phosphodiesterase family.,
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细胞定位:
Membrane ; Multi-pass membrane protein . Cytoplasm, cytosol .
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研究领域:
>>Purine metabolism ;
>>Metabolic pathways ;
>>cGMP-PKG signaling pathway ;
>>cAMP signaling pathway ;
>>Renin secretion ;
>>Morphine addiction
>>Metabolic pathways ;
>>cGMP-PKG signaling pathway ;
>>cAMP signaling pathway ;
>>Renin secretion ;
>>Morphine addiction
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信号通路
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货号: YP1737
规格
价格
货期
数量
200μL
￥4,680.00
两周
0
100μL
￥2,800.00
两周
0
50μL
￥1,500.00
两周
0
加入购物车
已收藏
收藏
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