SSH3 (Phospho Ser37) Rabbit pAb
-YP1511
主要信息
Target
SSH3 Phospho Ser37
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
74kD (Observed)
Conjugate/Modification
Phospho
货号: YP1511
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Human SSH3 (phospho-Ser37)
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
74kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
Synthesized phosho peptide around human SSH3 (Ser37)
展开内容
特异性:
This antibody detects endogenous levels of Human SSH3 (phospho-Ser37)
展开内容
基因名称:
SSH3 SSH3L
展开内容
蛋白名称:
SSH3 (Ser37)
展开内容
别名:
Protein phosphatase Slingshot homolog 3 ;
EC 3.1.3.48 ;
SSH-like protein 3 ;
SSH-3L ;
hSSH-3L ;
EC 3.1.3.48 ;
SSH-like protein 3 ;
SSH-3L ;
hSSH-3L ;
展开内容
背景:
The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al. , 2002 [PubMed 11832213]) .[supplied by OMIM , Mar 2008] ,
展开内容
功能:
Catalytic activity:A phosphoprotein + H (2) O = a protein + phosphate. ,Catalytic activity:Protein tyrosine phosphate + H (2) O = protein tyrosine + phosphate. ,Function:Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin , which subsequently binds to actin filaments and stimulates their disassembly. ,miscellaneous:Tyrosine phosphatase activity has not been demonstrated for this protein to date. ,PTM:Phosphorylated upon DNA damage , probably by ATM or ATR. ,similarity:Belongs to the protein-tyrosine phosphatase family. ,similarity:Contains 1 tyrosine-protein phosphatase domain. ,subunit:Does not bind to , or colocalize with , filamentous actin. ,
展开内容
细胞定位:
Cytoplasm , cytoskeleton . Nucleus .
展开内容
研究领域:
>>Axon guidance ;
>>Regulation of actin cytoskeleton
>>Regulation of actin cytoskeleton
展开内容
文献引用（{{totalcount}}）
货号: YP1511
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
×
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}