Cyclin B1 (Phospho Ser116) Rabbit pAb
-YP1305
主要信息
Target
Cyclin B1 Phospho Ser116
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB
MW
60kD (Observed)
Conjugate/Modification
Phospho
货号: YP1305
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Human Cyclin B1 (phospho-Ser116)
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
60kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
Synthesized phosho peptide around human Cyclin B1 (Ser116)
展开内容
特异性:
This antibody detects endogenous levels of Human Cyclin B1 (phospho-Ser116)
展开内容
基因名称:
CCNB1 CCNB
展开内容
蛋白名称:
G2/mitotic-specific cyclin-B1 (Ser116)
展开内容
别名:
CCNB1 ;
CCNB ;
G2/mitotic-specific cyclin-B1
CCNB ;
G2/mitotic-specific cyclin-B1
展开内容
背景:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF) . Two alternative transcripts have been found , a constitutively expressed transcript and a cell cycle-regulated transcript , that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq , Jul 2008] ,
展开内容
功能:
developmental stage:Accumulates steadily during G2 and is abruptly destroyed at mitosis. ,Function:Essential for the control of the cell cycle at the G2/M (mitosis) transition. ,PTM:Ubiquitinated by the SCF (NIPA) complex during interphase , leading to its destruction. Not ubiquitinated during G2/M phases. ,similarity:Belongs to the cyclin family. ,similarity:Belongs to the cyclin family. Cyclin AB subfamily. ,subunit:Interacts with the CDC2 protein kinase to form a serine/threonine kinase holoenzyme complex also known as maturation promoting factor (MPF) . The cyclin subunit imparts substrate specificity to the complex. Binds HEI10. Interacts with catalytically active RALBP1 and CDC2 during mitosis to form an endocytotic complex during interphase. ,
展开内容
细胞定位:
Cytoplasm. Nucleus. Cytoplasm , cytoskeleton , microtubule organizing center , centrosome.
展开内容
组织表达:
研究领域:
>>FoxO signaling pathway ;
>>Cell cycle ;
>>Oocyte meiosis ;
>>p53 signaling pathway ;
>>Cellular senescence ;
>>Progesterone-mediated oocyte maturation ;
>>Human immunodeficiency virus 1 infection
>>Cell cycle ;
>>Oocyte meiosis ;
>>p53 signaling pathway ;
>>Cellular senescence ;
>>Progesterone-mediated oocyte maturation ;
>>Human immunodeficiency virus 1 infection
展开内容
信号通路
文献引用（{{totalcount}}）
货号: YP1305
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
×
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}