GATA-3 (Phospho Ser308) Rabbit pAb
-YP1179
主要信息
Target
GATA-3 Phospho Ser308
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IF, ELISA
MW
48kD (Calculated)
Conjugate/Modification
Phospho
货号: YP1179
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-GATA-3 (S308) Polyclonal Antibody detects endogenous levels of GATA-3 protein only when phosphorylated at S308.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RLsAA
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
48kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human GATA3 around the phosphorylation site of Ser308. AA range:274-323
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特异性:
Phospho-GATA-3 (S308) Polyclonal Antibody detects endogenous levels of GATA-3 protein only when phosphorylated at S308.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RLsAA
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基因名称:
GATA3
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蛋白名称:
Trans-acting T-cell-specific transcription factor GATA-3
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别名:
GATA3 ;
Trans-acting T-cell-specific transcription factor GATA-3 ;
GATA-binding factor 3
Trans-acting T-cell-specific transcription factor GATA-3 ;
GATA-binding factor 3
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背景:
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009],
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功能:
Disease:Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome.,Function:Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:T-cells and endothelial cells.,
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细胞定位:
Nucleus.
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组织表达:
研究领域:
>>Th1 and Th2 cell differentiation ;
>>Th17 cell differentiation ;
>>Parathyroid hormone synthesis, secretion and action ;
>>Inflammatory bowel disease
>>Th17 cell differentiation ;
>>Parathyroid hormone synthesis, secretion and action ;
>>Inflammatory bowel disease
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信号通路
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货号: YP1179
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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