IL-9R (Phospho Ser519) Rabbit pAb
-YP0937
主要信息
Target
IL-9R Phospho Ser519
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
57kD (Observed)
Conjugate/Modification
Phospho
货号: YP0937
规格
价格
货期
数量
200μL
￥4,680.00
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0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-IL-9R (S519) Polyclonal Antibody detects endogenous levels of IL-9R protein only when phosphorylated at S519.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ARsWT
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
浓度
1 mg/ml
实测条带
57kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human IL-9R around the phosphorylation site of Ser519. AA range:472-521
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特异性:
Phospho-IL-9R (S519) Polyclonal Antibody detects endogenous levels of IL-9R protein only when phosphorylated at S519.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):ARsWT
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基因名称:
IL9R
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蛋白名称:
Interleukin-9 receptor
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别名:
IL9R ;
Interleukin-9 receptor ;
IL-9 receptor ;
IL-9R ;
CD antigen CD129
Interleukin-9 receptor ;
IL-9 receptor ;
IL-9R ;
CD antigen CD129
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背景:
The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9) . The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor , gamma (IL2RG) , a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins , which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9 , 10 , 16 , and 18 have been described. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq , Jul 2008] ,
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功能:
Domain:The box 1 motif is required for JAK interaction and/or activation. ,Domain:The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. ,Function:This is a receptor for interleukin-9. ,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 2 (PAR2) of X and Y chromosomes. ,similarity:Belongs to the type I cytokine receptor family. Type 4 subfamily. ,similarity:Contains 1 fibronectin type-III domain. ,
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细胞定位:
Cell membrane; Single-pass type I membrane protein. Secreted.
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组织表达:
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研究领域:
>>Cytokine-cytokine receptor interaction ;
>>JAK-STAT signaling pathway ;
>>Hematopoietic cell lineage
>>JAK-STAT signaling pathway ;
>>Hematopoietic cell lineage
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信号通路
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货号: YP0937
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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