p23 (Phospho Ser113) Rabbit pAb
-YP0673
主要信息
Target
p23 Phospho Ser113
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
24kD (Observed)
Conjugate/Modification
Phospho
货号: YP0673
规格
价格
货期
数量
200μL
￥4,680.00
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0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-p23 (S113) Polyclonal Antibody detects endogenous levels of p23 protein only when phosphorylated at S113.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):DDsDE
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
24kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human TEBP around the phosphorylation site of Ser113. AA range:79-128
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特异性:
Phospho-p23 (S113) Polyclonal Antibody detects endogenous levels of p23 protein only when phosphorylated at S113.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):DDsDE
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基因名称:
PTGES3
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蛋白名称:
Prostaglandin E synthase 3
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别名:
PTGES3 ;
P23 ;
TEBP ;
Prostaglandin E synthase 3 ;
Cytosolic prostaglandin E2 synthase ;
cPGES ;
Hsp90 co-chaperone ;
Progesterone receptor complex p23 ;
Telomerase-binding protein p23
P23 ;
TEBP ;
Prostaglandin E synthase 3 ;
Cytosolic prostaglandin E2 synthase ;
cPGES ;
Hsp90 co-chaperone ;
Progesterone receptor complex p23 ;
Telomerase-binding protein p23
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背景:
This gene encodes an enzyme that converts prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). This protein functions as a co-chaperone with heat shock protein 90 (HSP90), localizing to response elements in DNA and disrupting transcriptional activation complexes. Alternative splicing results in multiple transcript variants. There are multiple pseudogenes of this gene on several different chromosomes. [provided by RefSeq, Feb 2016],
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功能:
Catalytic activity:(5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate.,Function:Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.,pathway:Lipid metabolism; prostaglandin biosynthesis.,similarity:Belongs to the p23/wos2 family.,similarity:Contains 1 CS domain.,subunit:Binds to telomerase and to the progesterone receptor.,
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细胞定位:
Cytoplasm .
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研究领域:
>>Arachidonic acid metabolism ;
>>Metabolic pathways ;
>>Chemical carcinogenesis - receptor activation
>>Metabolic pathways ;
>>Chemical carcinogenesis - receptor activation
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货号: YP0673
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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