Na+/K+-ATPase α1 (Phospho Ser23) Rabbit pAb
-YP0563
主要信息
Target
Na+/K+-ATPase α1 Phospho Ser23
Host Species
Rabbit
Reactivity
Rat
Applications
WB, IF, ELISA
MW
113kD (Observed)
Conjugate/Modification
Phospho
货号: YP0563
规格
价格
货期
数量
200μL
￥4,680.00
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0
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￥2,800.00
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详细信息
推荐稀释比
WB 1:500-1:2000; IF 1:100-1:300; ELISA 1:5000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-Na+/K+-ATPase α1 (S23) Polyclonal Antibody detects endogenous levels of Na+/K+-ATPase α1 protein only when phosphorylated at S23.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):KKsKK
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
113kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from rat ATP1 alpha1/Na+K+ ATPase1 around the phosphorylation site of Ser23. AA range:15-64
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特异性:
Phospho-Na+/K+-ATPase α1 (S23) Polyclonal Antibody detects endogenous levels of Na+/K+-ATPase α1 protein only when phosphorylated at S23.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):KKsKK
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基因名称:
ATP1A1
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蛋白名称:
Sodium/potassium-transporting ATPase subunit alpha-1
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别名:
ATP1A1 ;
Sodium/potassium-transporting ATPase subunit alpha-1 ;
Na ;
+ ;
/K ;
+ ;
ATPase alpha-1 subunit ;
Sodium pump subunit alpha-1
Sodium/potassium-transporting ATPase subunit alpha-1 ;
Na ;
+ ;
/K ;
+ ;
ATPase alpha-1 subunit ;
Sodium pump subunit alpha-1
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背景:
The ATPase Na+/K+ transporting subunit alpha 1 encoded by ATP1A1 belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.
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信号通路
Organismal Systems >> Endocrine system >> Insulin secretion
Organismal Systems >> Endocrine system >> Thyroid hormone signaling pathway
Organismal Systems >> Endocrine system >> Aldosterone synthesis and secretion
Organismal Systems >> Circulatory system >> Cardiac muscle contraction
Organismal Systems >> Circulatory system >> Adrenergic signaling in cardiomyocytes
Environmental Information Processing >> Signal transduction >> cAMP signaling pathway
Environmental Information Processing >> Signal transduction >> cGMP-PKG signaling pathway
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货号: YP0563
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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