ITGB6 (PT0428R) PT™ Rabbit mAb
-YM8270
主要信息
Target
ITGB6
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, IP, ELISA
MW
86kD (Calculated)
86kD (Observed)
Conjugate/Modification
Unmodified
货号: YM8270
规格
价格
货期
数量
200μL
￥3,580.00
现货
0
100μL
￥1,960.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
IHC 1:2000-1:10000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200;
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
86kD
实测条带
86kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT0428R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
ITGB6
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蛋白名称:
Integrin beta-6
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背景:
This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
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功能:
Function:Integrin alpha-V/beta-6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands.,similarity:Belongs to the integrin beta chain family.,similarity:Contains 1 VWFA domain.,subunit:Heterodimer of an alpha and a beta subunit. Beta-6 associates with alpha-V. Interacts with FLNB. Alpha-V/beta-6 binds to foot-and-mouth disease virus (FMDV) VP1 protein, coxsackievirus A9, coxsackievirus B1 capsid proteins and acts as a receptor for these viruses.,
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细胞定位:
Membrane
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组织表达:
研究领域:
>>PI3K-Akt signaling pathway ;
>>Focal adhesion ;
>>ECM-receptor interaction ;
>>Regulation of actin cytoskeleton ;
>>Human papillomavirus infection ;
>>Hypertrophic cardiomyopathy ;
>>Arrhythmogenic right ventricular cardiomyopathy ;
>>Dilated cardiomyopathy
>>Focal adhesion ;
>>ECM-receptor interaction ;
>>Regulation of actin cytoskeleton ;
>>Human papillomavirus infection ;
>>Hypertrophic cardiomyopathy ;
>>Arrhythmogenic right ventricular cardiomyopathy ;
>>Dilated cardiomyopathy
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信号通路
Cellular Processes >> Cellular community - eukaryotes >> Focal adhesion
Cellular Processes >> Cell motility >> Regulation of actin cytoskeleton
Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway
Environmental Information Processing >> Signaling molecules and interaction >> ECM-receptor interaction
文献引用（{{totalcount}}）
货号: YM8270
规格
价格
货期
数量
200μL
￥3,580.00
现货
0
100μL
￥1,960.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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