Calnexin Mouse mAb
-YM0089
主要信息
Target
Calnexin
Host Species
Mouse
Reactivity
Human
Applications
WB, IF, ELISA
MW
68kD (Calculated)
Conjugate/Modification
Unmodified
货号: YM0089
规格
价格
货期
数量
200μL
￥5,880.00
一周
0
100μL
￥3,200.00
一周
0
50μL
￥2,000.00
一周
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Calnexin Monoclonal Antibody detects endogenous levels of Calnexin protein.
纯化工艺
Affinity purification
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
68kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
10E1
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抗原&靶点信息
免疫原:
Synthetic peptide corresponding to aa (CEAAEERPWLWVVYILTVAL) of human Calnexin, conjugated to KLH.
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特异性:
Calnexin Monoclonal Antibody detects endogenous levels of Calnexin protein.
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基因名称:
CANX
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蛋白名称:
Calnexin
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别名:
CANX ;
Calnexin ;
IP90 ;
Major histocompatibility complex class I antigen-binding protein p88 ;
p90
Calnexin ;
IP90 ;
Major histocompatibility complex class I antigen-binding protein p88 ;
p90
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背景:
This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],
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功能:
Function:Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins.,online information:Calnexin entry,similarity:Belongs to the calreticulin family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,
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细胞定位:
Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Endoplasmic reticulum . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545, PubMed:17081065). The palmitoylated form preferentially localizes to the perinuclear rough ER (PubMed:22314232). .
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组织表达:
B-cell lymphoma,Epithelium,Fibroblast,Keratinocyte,Kidney,Liver,Lymph,Placenta,Platelet,
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研究领域:
>>Protein processing in endoplasmic reticulum ;
>>Phagosome ;
>>Antigen processing and presentation ;
>>Thyroid hormone synthesis ;
>>Human T-cell leukemia virus 1 infection
>>Phagosome ;
>>Antigen processing and presentation ;
>>Thyroid hormone synthesis ;
>>Human T-cell leukemia virus 1 infection
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信号通路
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货号: YM0089
规格
价格
货期
数量
200μL
￥5,880.00
一周
0
100μL
￥3,200.00
一周
0
50μL
￥2,000.00
一周
0
加入购物车
已收藏
收藏
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