Carbonic Anhydrase 9 (ABT138) Rabbit mAb
-YM6258
主要信息
Target
CA IX
Host Species
Rabbit
Reactivity
Human
Applications
IHC
Conjugate/Modification
Unmodified
货号: YM6258
规格
价格
货期
数量
200μL
￥3,580.00
现货
0
100μL
￥1,960.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
详细信息
推荐稀释比
IHC 1:200-1:400
Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
储存
-15°C to -25°C/1 year (Do not lower than -25°C)
修饰
Unmodified
克隆性
Monoclonal
克隆号
ABT138
同种型
IgG, Kappa
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
The specific immunogen used to produce this antibody is proprietary information.
展开内容
特异性:
Endogenous
展开内容
基因名称:
CA9
展开内容
蛋白名称:
Carbonic anhydrase 9
展开内容
别名:
G250 ;
MN ;
Carbonic anhydrase 9 ;
Carbonate dehydratase IX ;
Carbonic anhydrase IX ;
CA-IX ;
CAIX ;
Membrane antigen MN ;
P54/58N ;
Renal cell carcinoma-associated antigen G250 ;
RCC-associated antigen G250 ;
pMW1
MN ;
Carbonic anhydrase 9 ;
Carbonate dehydratase IX ;
Carbonic anhydrase IX ;
CA-IX ;
CAIX ;
Membrane antigen MN ;
P54/58N ;
Renal cell carcinoma-associated antigen G250 ;
RCC-associated antigen G250 ;
pMW1
展开内容
背景:
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes , including respiration , calcification , acid-base balance , bone resorption , and the formation of aqueous humor , cerebrospinal fluid , saliva , and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma , but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization , however , radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq , Jun 2014] ,
展开内容
功能:
Catalytic activity:H (2) CO (3) = CO (2) + H (2) O. ,cofactor:Zinc. ,Function:Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia. ,induction:By hypoxia. ,PTM:Asn-346 bears high-mannose type glycan structures. ,similarity:Belongs to the alpha-carbonic anhydrase family. ,subcellular location:Found on the surface microvilli and in the nucleus , particularly in nucleolus. ,subunit:Forms oligomers linked by disulfide bonds. ,tissue specificity:Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa. ,
展开内容
细胞定位:
Membranous
展开内容
研究领域:
>>Nitrogen metabolism ;
>>Metabolic pathways
>>Metabolic pathways
展开内容
文献引用（{{totalcount}}）
货号: YM6258
规格
价格
货期
数量
200μL
￥3,580.00
现货
0
100μL
￥1,960.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
Recently Viewed Products
Clear all
×
Toggle night Mode
{{pinfoXq.title || ''}}
Catalog: {{pinfoXq.catalog || ''}}
Filter：
All
{{item.name}}
{{pinfo.title}}
-{{pinfo.catalog}}
主要信息
Target
{{pinfo.target}}
Reactivity
{{pinfo.react}}
Applications
{{pinfo.applicat}}
Conjugate/Modification
{{pinfo.coupling}}/{{pinfo.modific}}
MW (kDa)
{{pinfo.mwcalc}}
Host Species
{{pinfo.hostspec}}
Isotype
{{pinfo.isotype}}
产品 {{index}}/{{pcount}}
上一个产品
下一个产品
{{pvTitle}}
滚轮缩放图片
{{pvDescr}}