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R

AF-10 (PT1742R) PT™ Rabbit mAb

-YM9584

hot 5 2 10
主要信息
Target

AF-10

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF, ELISA

MW

113kD (Calculated)

130kD (Observed)

Conjugate/Modification

Unmodified

货号: YM9584
规格
价格
货期
数量
200μL
¥3,580.00
现货

0

100μL
¥1,960.00
现货

0

40μL
¥960.00
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0

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详细信息
推荐稀释比
IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000;
Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004)
组成
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
特异性
Endogenous
纯化工艺
Protein A
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
理论分子量
113kD
实测条带
130kD
修饰
Unmodified
克隆性
Monoclonal
克隆号
PT1742R
同种型
IgG,Kappa
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抗原&靶点信息
特异性:
Endogenous
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基因名称:
MLLT10
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蛋白名称:
Protein AF-10
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别名:
MLLT10 ;
AF10 ;
Protein AF-10 ;
ALL1-fused gene from chromosome 10 protein
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数据库链接:
Organism 基因 ID SwissProt
Human 8028; P55197;
Mouse 17354; O54826;
背景:
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10(MLLT10) Homo sapiens This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010],
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功能:
Disease:A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t(10;11)(p12;q23) with MLL/HRX. The result is a rogue activator protein.,Disease:A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t(10;11)(p13;q14) with PICALM.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 PHD-type zinc fingers.,tissue specificity:Expressed abundantly in testis.,
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细胞定位:
Nucleus .
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组织表达:
货号: YM9584
规格
价格
货期
数量
200μL
¥3,580.00
现货

0

100μL
¥1,960.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询
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