Endogenous

CD69

Early activation antigen CD69

CD69 ;
CLEC2C ;
Early activation antigen CD69 ;
Activation inducer molecule ;
AIM ;
BL-AC/P26 ;
C-type lectin domain family 2 member C ;
EA1 ;
Early T-cell activation antigen p60 ;
GP32/28 ;
Leukocyte surface antigen Leu-23 ;
MLR-3 ;
CD antigen CD69

This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011],

developmental stage:Earliest inducible cell surface glycoprotein acquired during lymphoid activation.,Function:Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.,induction:By antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes. By interaction of IL-2 with the p75 IL-2R on the surface of NK cells.,online information:CD69,PTM:Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.,similarity:Contains 1 C-type lectin domain.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.,

Membrane; Single-pass type II membrane protein.