CD142 (PN0245) Nb-FC recombinant antibody
-YA0009
主要信息
Target
CD142
Reactivity
Human
Applications
ELISA
Conjugate/Modification
Unmodified
货号: YA0009
规格
价格
货期
数量
200μg
￥3,780.00
现货
0
100μg
￥2,300.00
现货
0
40μg
￥960.00
现货
0
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详细信息
推荐稀释比
ELISA 1:5000-100000
组成
Phosphate-buffered solution
来源
Camel, chimeric fusion of Nanobody (VHH) and mouse IgG1 Fc domain , recombinantly produced from 293F cell
特异性
This recombinant monoclonal antibody can detects endogenous levels of CD142 protein.
纯化工艺
Recombinant Expression and Affinity purified
储存
-15°C to -25°C/1 year (Avoid freeze / thaw cycles)
浓度
Please check the information on the tube
修饰
Unmodified
克隆号
PN0245
同种型
IgG2a, Kappa
相关产品
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
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抗原&靶点信息
免疫原:
Purified recombinant Human CD142
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特异性:
This recombinant monoclonal antibody can detects endogenous levels of CD142 protein.
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基因名称:
F3
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蛋白名称:
Tissue factor (TF) (Coagulation factor III) (Thromboplastin) (CD antigen CD142)
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别名:
Coagulation Factor III ;
Tissue Factor ;
TF ;
Thromboplastin ;
platelet tissue factor ;
factor III ;
factor 3 ;
F3 ;
F-3 ;
TFA
Tissue Factor ;
TF ;
Thromboplastin ;
platelet tissue factor ;
factor III ;
factor 3 ;
F3 ;
F-3 ;
TFA
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背景:
CD142 , also known as Tissue Factor (TF) , Coagulation Factor III , and Thromboplastin , is a 45 kD type I transmembrane glycoprotein. It is expressed on the surface of a variety of cells that are physically separated from the circulating blood which include smooth muscle cells , fibroblasts , keratinocytes , glomerular epithelial cells (cytoplasmic inclusions) , astrocytes , myocardium , liver stromal cells , pancreas cells , and is also expressed on activated monocytes and stimulated endothelial cells. CD142 is a high-affinity receptor for coagulation factor VII and initiates the extrinsic pathway of blood coagulation. CD142 also plays an important role in a variety of diseases such as sepsis , atherosclerosis , and cancer.
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功能:
Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
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细胞定位:
[Isoform 1]: Membrane ; Single-pass type I membrane protein .; [Isoform 2]: Secreted .
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组织表达:
文献引用（{{totalcount}}）
货号: YA0009
规格
价格
货期
数量
200μg
￥3,780.00
现货
0
100μg
￥2,300.00
现货
0
40μg
￥960.00
现货
0
加入购物车
已收藏
收藏
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