EAAT2 Rabbit pAb
-YT7964
主要信息
Target
EAAT2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, ELISA
MW
63kD (Calculated)
Conjugate/Modification
Unmodified
货号: YT7964
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
WB 1:1000-2000; ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Human,Rat,Mouse EAA2
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
63kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
相关产品
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Goat Anti Mouse IgG(H+L) (HRP)
RS0001
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Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
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Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human EAA2
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特异性:
This antibody detects endogenous levels of Human,Rat,Mouse EAA2
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基因名称:
SLC1A2 EAAT2 GLT1
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蛋白名称:
Excitatory amino acid transporter 2
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别名:
Excitatory amino acid transporter 2 ;
Glutamate/aspartate transporter II ;
Sodium-dependent glutamate/aspartate transporter 2 ;
Solute carrier family 1 member 2 ;
Glutamate/aspartate transporter II ;
Sodium-dependent glutamate/aspartate transporter 2 ;
Solute carrier family 1 member 2 ;
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背景:
This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010],
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功能:
Function:Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.,PTM:Glycosylated.,similarity:Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family.,subunit:Homotrimer. Interacts with JUB.,
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细胞定位:
Cell membrane ; Multi-pass membrane protein .
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研究领域:
>>Synaptic vesicle cycle ;
>>Glutamatergic synapse ;
>>Amyotrophic lateral sclerosis ;
>>Huntington disease
>>Glutamatergic synapse ;
>>Amyotrophic lateral sclerosis ;
>>Huntington disease
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信号通路
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货号: YT7964
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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