BDNF Rabbit pAb

联系我们

400-8787-807

积分商城

快速订购

产品

抗体

一抗二抗精品兔多克隆抗体精品小鼠单克隆抗体重组兔单克隆抗体磷酸化抗体甲基化抗体乙酰化抗体瓜氨酸化抗体泛修饰性抗体

流式细胞术抗体纳米抗体hot IHC抗体/即用型直标一抗同型对照抗体内参抗体标签抗体 Polymer酶标二抗hot IP专用二抗

试剂盒

mIHC/mIF检测试剂盒 IHC抗体试剂盒 Sandwich ELISA试剂盒 Cell Based ELISA试剂盒免疫组化试剂盒

实验试剂

Western Blot实验试剂 IHC辅助试剂 IF辅助试剂 mIHC/mIF辅助试剂实验佐剂阳性对照

重组蛋白

真核重组蛋白原核重组蛋白
研究领域

癌症免疫学心血管细胞生物学表观遗传学

干细胞代谢神经科学微生物学发育生物学
信号通路

查看所有细胞信号转导通路
定制服务

抗体定制服务病理检测服务蛋白免疫功能服务蛋白表达服务激光切割服务
支持信息

实验Protocols

Western Blot IHC IF/ICC IP

实验疑难解答

Western Blot疑难排除 IHC疑难排除 IF/ICC疑难排除 ELISA 疑难排除其他常见问题

网站资源

基因&蛋白信息库文献检索科学网站

视频与学术研讨会

实验教学视频学术会议

宣传资料

产品/专题刊物文献中心
公司简介

关于我们加入我们合作伙伴联系我们

我的购物车

Chinese

Chinese English

抗体大放送！抗体买一送四，全线产品买二送一

-YT7904

说明书

SDS

FAQ

主要信息

Target

BDNF

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, ELISA

27kD (Calculated)

Conjugate/Modification

Unmodified

货号: YT7904

规格

价格

货期

数量

200μL

￥3,780.00

现货

100μL

￥2,300.00

现货

40μL

￥960.00

现货

加入购物车

已收藏

定制服务咨询

详细信息相关产品抗原&靶点信息信号通路

详细信息

推荐稀释比

WB 1:1000-2000; ELISA 1:5000-20000

组成

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

特异性

This antibody detects endogenous levels of Human,Mouse,Rat BDNF

纯化工艺

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

储存

-15°C to -25°C/1 year(Do not lower than -25°C)

浓度

1 mg/ml

理论分子量

27kD

修饰

Unmodified

克隆性

Polyclonal

同种型

IgG

相关产品

Secondary Antibodies

Goat Anti Mouse IgG(H+L) (HRP)

RS0001

预览→

Secondary Antibodies

Goat Anti Rabbit IgG(H+L) (HRP)

RS0002

预览→

Primary Antibodies

β-actin (PTR2364) Mouse mAb

YM3028

预览→

Primary Antibodies

GAPDH (PTR2304) Mouse mAb

YM3029

预览→

抗原&靶点信息

免疫原:

Synthesized peptide derived from human BDNF. AA range:1-130

展开内容

特异性:

This antibody detects endogenous levels of Human,Mouse,Rat BDNF

展开内容

基因名称:

BDNF

展开内容

蛋白名称:

BDNF(Brain Derived Neurotrophic Factor)

展开内容

别名:

Brain-derived neurotrophic factor ;
BDNF ;
Abrineurin ;

展开内容

数据库链接:

Organism	基因 ID	SwissProt
Human	627;	P23560;
Mouse		P21237;
Rat		P23363;

背景:

This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders. [provided by RefSeq, Nov 2015]

展开内容

功能:

Important signaling molecule that activates signaling cascades downstream of NTRK2 (PubMed:11152678). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability

展开内容

细胞定位:

Secreted .; [BDNF precursor form]: Secreted . A proportion of BDNF is secreted as immature precursor (proBDNF). .

展开内容

组织表达:

Detected in blood plasma and in saliva (at protein level) (PubMed:11152678, PubMed:19467646). Brain. Highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. Also expressed in heart, lung, skeletal muscle, testis, prostate and placenta

展开内容

研究领域:

>>MAPK signaling pathway ;
>>Ras signaling pathway ;
>>cAMP signaling pathway ;
>>PI3K-Akt signaling pathway ;
>>Neurotrophin signaling pathway ;
>>Huntington disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Cocaine addiction ;
>>Alcoholism

展开内容

信号通路