This gene encodes a member of the glycerophosphodiester phosphodiesterase family of enzymes that catalyze the hydrolysis of deacylated glycerophospholipids to glycerol phosphate and alcohol. The encoded protein is localized to the cytoplasm and concentrates near the perinuclear region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
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功能:
similarity:Belongs to the glycerophosphoryl diester phosphodiesterase family.,similarity:Contains 1 GDPD domain.,tissue specificity:Detected in placenta, liver, kidney, pancreas, spleen, thymus, ovary, small intestine and peripheral blood leukocytes.,
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细胞定位:
Cytoplasm . Membrane ; Multi-pass membrane protein . Cytoplasm, perinuclear region . Endoplasmic reticulum . Concentrated at the perinuclear region and the cell periphery (PubMed:18991142). .
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组织表达:
Widely expressed with high expression level in testis.