CD11c Rabbit pAb
-YT5924
主要信息
Target
Integrin αX
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
IHC, IF, ELISA
Conjugate/Modification
Unmodified
货号: YT5924
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
The antibody detects endogenous Integrin αX
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthetic peptide from human protein at AA range: 920-980
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特异性:
The antibody detects endogenous Integrin αX
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基因名称:
ITGAX CD11C
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蛋白名称:
Integrin alpha-X (CD11 antigen-like family member C) (Leu M5) (Leukocyte adhesion glycoprotein p150,95 alpha chain) (Leukocyte adhesion receptor p150,95) (CD antigen CD11c)
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别名:
Integrin alpha-X ;
CD11 antigen-like family member C ;
Leu M5 ;
Leukocyte adhesion glycoprotein p150,95 alpha chain ;
Leukocyte adhesion receptor p150,95 ;
CD antigen CD11c ;
CD11 antigen-like family member C ;
Leu M5 ;
Leukocyte adhesion glycoprotein p150,95 alpha chain ;
Leukocyte adhesion receptor p150,95 ;
CD antigen CD11c ;
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背景:
integrin subunit alpha X(ITGAX) Homo sapiens This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013],
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功能:
Domain:The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.,Function:Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 1 VWFA domain.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. Alpha-X associates with beta-2.,tissue specificity:Predominantly expressed in monocytes and granulocytes.,
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细胞定位:
Membrane; Single-pass type I membrane protein.
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组织表达:
Predominantly expressed in monocytes and granulocytes.
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研究领域:
>>Complement and coagulation cascades ;
>>Regulation of actin cytoskeleton ;
>>Tuberculosis
>>Regulation of actin cytoskeleton ;
>>Tuberculosis
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信号通路
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货号: YT5924
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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