The antiserum was produced against synthesized peptide derived from the N-terminal region of human CLEC11A. AA range:1-50

SCGF Polyclonal Antibody detects endogenous levels of SCGF protein.

CLEC11A

C-type lectin domain family 11 member A

CLEC11A ;
CLECSF3 ;
LSLCL ;
SCGF ;
C-type lectin domain family 11 member A ;
C-type lectin superfamily member 3 ;
Lymphocyte secreted C-type lectin ;
Stem cell growth factor ;
p47

This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008],

developmental stage:In the bone marrow, expression is limited to immature neutrophils. Expression was not detected in circulating mature neutrophils.,Function:Stimulates the proliferation and differentiation of hematopoietic precursor cells from various lineages, including erythrocytes, lymphocytes, granulocytes and macrophages. Acts synergistically with other cytokines, including IL-3, GCSF, GMCSF and FLT3 ligand. Suppresses SCF-stimulated erythrocyte proliferation.,online information:Stem cell growth factor,PTM:O-glycosylated. Probably sulfated on the O-glycans.,similarity:Contains 1 C-type lectin domain.,tissue specificity:Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.,

Cytoplasm . Secreted .

Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.