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CD206 Rabbit pAb

-YT5640

2
主要信息
Target

CD206

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF, ELISA

MW

170kD (Observed)

Conjugate/Modification

Unmodified

货号: YT5640
规格
价格
货期
数量
200μL
¥3,780.00
一个月

0

100μL
¥2,300.00
一个月

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40μL
¥960.00
一个月

0

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详细信息
推荐稀释比
WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:100-300; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
CD206 Polyclonal Antibody detects endogenous levels of CD206 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
170kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from the Internal region of human MRC1. AA range:341-390
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特异性:
CD206 Polyclonal Antibody detects endogenous levels of CD206 protein.
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基因名称:
MRC1
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蛋白名称:
Macrophage mannose receptor 1
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别名:
MRC1 ;
CLEC13D ;
CLEC13DL ;
MRC1L1 ;
Macrophage mannose receptor 1 ;
MMR ;
C-type lectin domain family 13 member D ;
C-type lectin domain family 13 member D-like ;
Macrophage mannose receptor 1-like protein 1 ;
CD206
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数据库链接:
Organism 基因 ID SwissProt
Human 4360; P22897;
Mouse 17533; Q61830;
背景:
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015],
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功能:
Function:Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.,miscellaneous:CRDs 1-3 have at most very weak affinity for carbohydrate. CRD 4 shows the highest affinity binding and has multispecificity for a variety of monosaccharides. At least 3 CRDs (4, 5, and 7) are required for high affinity binding and endocytosis of multivalent glycoconjugates.,online information:Macrophage mannose receptor,similarity:Contains 1 fibronectin type-II domain.,similarity:Contains 1 ricin B-type lectin domain.,similarity:Contains 8 C-type lectin domains.,
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细胞定位:
Endosome membrane ; Single-pass type I membrane protein . Cell membrane ; Single-pass type I membrane protein .
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组织表达:
Milk,Placenta,Testis,
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研究领域:
>>Phagosome ;
>>Tuberculosis
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货号: YT5640
规格
价格
货期
数量
200μL
¥3,780.00
一个月

0

100μL
¥2,300.00
一个月

0

40μL
¥960.00
一个月

0

加入购物车

已收藏

收藏

定制服务咨询

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