LASP-1 Rabbit pAb
-YT5234
主要信息
Target
LASP-1
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
MW
28kD (Observed)
Conjugate/Modification
Unmodified
货号: YT5234
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
LASP-1 Polyclonal Antibody detects endogenous levels of LASP-1 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
28kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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YM3028
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from the Internal region of human LASP1. AA range:51-100
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特异性:
LASP-1 Polyclonal Antibody detects endogenous levels of LASP-1 protein.
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基因名称:
LASP1
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蛋白名称:
LIM and SH3 domain protein 1
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别名:
LASP1 ;
MLN50 ;
LIM and SH3 domain protein 1 ;
LASP-1 ;
Metastatic lymph node gene 50 protein ;
MLN 50
MLN50 ;
LIM and SH3 domain protein 1 ;
LASP-1 ;
Metastatic lymph node gene 50 protein ;
MLN 50
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背景:
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer. [provided by RefSeq, Oct 2012],
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功能:
Function:Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.,PTM:Phosphorylated.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 nebulin repeats.,subcellular location:Associated with the F-actin rich cortical cytoskeleton.,subunit:Interacts with F-actin.,
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细胞定位:
Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Associated with the F-actin rich cortical cytoskeleton. .
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组织表达:
Epithelium,Liver,Mammary carcinoma,Platelet,Skin,T-cell,
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文献引用（{{totalcount}}）
货号: YT5234
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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