BNIP-3 Rabbit pAb
-YT5154
主要信息
Target
BNIP-3
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
22kD (Observed)
Conjugate/Modification
Unmodified
货号: YT5154
规格
价格
货期
数量
200μL
￥3,780.00
一个月
0
100μL
￥2,300.00
一个月
0
40μL
￥960.00
一个月
0
加入购物车
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC: 1:100-300; ELISA 1:20000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
BNIP-3 Polyclonal Antibody detects endogenous levels of BNIP-3 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
22kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from the Internal region of human BNIP3. AA range:71-120
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特异性:
BNIP-3 Polyclonal Antibody detects endogenous levels of BNIP-3 protein.
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基因名称:
BNIP3
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蛋白名称:
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
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别名:
BNIP3 ;
NIP3 ;
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
NIP3 ;
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3
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背景:
This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. [provided by RefSeq, Dec 2014],
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功能:
Function:Apoptosis-inducing protein that, which can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2.,similarity:Belongs to the NIP3 family.,subcellular location:Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope.,subunit:Homodimer. Binds to BCL2. Interacts with BNIP3L. Also can interact with adenovirus E1B 19 kDa protein or Epstein-Barr virus BHRF1.,
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细胞定位:
Mitochondrion. Mitochondrion outer membrane; Single-pass membrane protein. Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria. Colocalizes with SPATA18 at the mitochondrion outer membrane.
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组织表达:
B-cell,Brain,Cerebellum,Kidney,Testis,
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研究领域:
>>FoxO signaling pathway ;
>>Mitophagy - animal ;
>>Autophagy - animal ;
>>Shigellosis ;
>>Legionellosis
>>Mitophagy - animal ;
>>Autophagy - animal ;
>>Shigellosis ;
>>Legionellosis
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信号通路
文献引用（{{totalcount}}）
货号: YT5154
规格
价格
货期
数量
200μL
￥3,780.00
一个月
0
100μL
￥2,300.00
一个月
0
40μL
￥960.00
一个月
0
加入购物车
已收藏
收藏
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