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SCP-3 Rabbit pAb

-YT5117

2 5
主要信息
Target

SCP-3

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

WB, ELISA, IHC

MW

27kD (Observed)

Conjugate/Modification

Unmodified

货号: YT5117
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
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0

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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
SCP-3 Polyclonal Antibody detects endogenous levels of SCP-3 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
27kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from the Internal region of human SCP-3.
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特异性:
SCP-3 Polyclonal Antibody detects endogenous levels of SCP-3 protein.
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基因名称:
SYCP3
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蛋白名称:
Synaptonemal complex protein 3
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别名:
SYCP3 ;
SCP3 ;
Synaptonemal complex protein 3 ;
SCP-3
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数据库链接:
Organism 基因 ID SwissProt
Human 50511; Q8IZU3;
Mouse 20962; P70281;
背景:
This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2010],
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功能:
Disease:Defects in SYCP3 are associated with azoospermia due to perturbations of meiosis [MIM:270960].,Function:Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development.,similarity:Belongs to the XLR/SYCP3 family.,subcellular location:In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed.,subunit:Interacts with SYCP2.,tissue specificity:Testis-specific.,
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细胞定位:
Nucleus . Chromosome . Chromosome, centromere . It is present in early unpaired cores, in the lateral domains of the synaptonemal complex and in the chromosome cores when they separate at diplotene. It is found axial to the metaphase I chromosomes and in association with pairs of sister centromeres. The centromere-associated protein becomes dissociated from the centromeres at anaphase II and is not found in mitotic metaphase centromeres. .
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组织表达:
Testis-specific.
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研究领域:
>>Homologous recombination
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货号: YT5117
规格
价格
货期
数量
200μL
¥3,780.00
现货

0

100μL
¥2,300.00
现货

0

40μL
¥960.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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