VE-Cadherin Rabbit pAb
-YT4869
主要信息
Target
VE-Cadherin
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
120kD (Observed)
Conjugate/Modification
Unmodified
货号: YT4869
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
VE-Cadherin Polyclonal Antibody detects endogenous levels of VE-Cadherin protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
120kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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ELISA Kits
Total VE-Cadherin Cell-Based Colorimetric ELISA Kit
KA4320C
预览→
抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human CDH5. AA range:697-746
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特异性:
VE-Cadherin Polyclonal Antibody detects endogenous levels of VE-Cadherin protein.
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基因名称:
CDH5
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蛋白名称:
Cadherin-5
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别名:
CDH5 ;
Cadherin-5 ;
7B4 antigen ;
Vascular endothelial cadherin ;
VE-cadherin ;
CD antigen CD144
Cadherin-5 ;
7B4 antigen ;
Vascular endothelial cadherin ;
VE-cadherin ;
CD antigen CD144
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背景:
This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. [provided by RefSeq, Nov 2015],
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功能:
Function:Cadherins are calcium dependent cell adhesion proteins.,Function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton.,similarity:Contains 5 cadherin domains.,subcellular location:Found at cell-cell boundaries and probably at cell-matrix boundaries.,tissue specificity:Endothelial tissues and brain.,
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细胞定位:
Cell junction . Cell membrane ; Single-pass type I membrane protein . Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions. .
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组织表达:
Endothelial tissues and brain.
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研究领域:
>>Cell adhesion molecules ;
>>Leukocyte transendothelial migration ;
>>Fluid shear stress and atherosclerosis
>>Leukocyte transendothelial migration ;
>>Fluid shear stress and atherosclerosis
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信号通路
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货号: YT4869
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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