TIMP-2 Rabbit pAb
-YT4659
主要信息
Target
TIMP-2
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
25kD (Observed)
Conjugate/Modification
Unmodified
货号: YT4659
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
TIMP-2 Polyclonal Antibody detects endogenous levels of TIMP-2 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
25kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
相关产品
Primary Antibodies
TIMP-2 Rabbit pAb
YT4659
预览→
ELISA Kits
Human TIMP-2 ELISA Kit
KE1167
预览→
ELISA Kits
Total TIMP-2 Cell-Based Colorimetric ELISA Kit
KA3398C
预览→
Secondary Antibodies
Goat Anti Mouse IgG(H+L) (HRP)
RS0001
预览→
Secondary Antibodies
Goat Anti Rabbit IgG(H+L) (HRP)
RS0002
预览→
Primary Antibodies
β-actin (PTR2364) Mouse mAb
YM3028
预览→
Primary Antibodies
GAPDH (PTR2304) Mouse mAb
YM3029
预览→
抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human TIMP2. AA range:21-70
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特异性:
TIMP-2 Polyclonal Antibody detects endogenous levels of TIMP-2 protein.
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基因名称:
TIMP2
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蛋白名称:
Metalloproteinase inhibitor 2
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别名:
TIMP2 ;
Metalloproteinase inhibitor 2 ;
CSC-21K ;
Tissue inhibitor of metalloproteinases 2 ;
TIMP-2
Metalloproteinase inhibitor 2 ;
CSC-21K ;
Tissue inhibitor of metalloproteinases 2 ;
TIMP-2
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背景:
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008],
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功能:
Function:Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19.,PTM:The activity of TIMP2 is dependent on the presence of disulfide bonds.,similarity:Belongs to the protease inhibitor I35 (TIMP) family.,similarity:Contains 1 NTR domain.,
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细胞定位:
Secreted.
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组织表达:
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货号: YT4659
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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