TAT Rabbit pAb
-YT4543
主要信息
Target
TAT
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
MW
50kD (Calculated)
Conjugate/Modification
Unmodified
货号: YT4543
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
TAT Polyclonal Antibody detects endogenous levels of TAT protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
50kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human TAT. AA range:255-304
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特异性:
TAT Polyclonal Antibody detects endogenous levels of TAT protein.
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基因名称:
TAT
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蛋白名称:
Tyrosine aminotransferase
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别名:
TAT ;
Tyrosine aminotransferase ;
TAT ;
L-tyrosine:2-oxoglutarate aminotransferase
Tyrosine aminotransferase ;
TAT ;
L-tyrosine:2-oxoglutarate aminotransferase
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背景:
This nuclear gene encodes a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate. Mutations in this gene cause tyrosinemia (type II, Richner-Hanhart syndrome), a disorder accompanied by major skin and corneal lesions, with possible mental retardation. A regulator gene for tyrosine aminotransferase is X-linked. [provided by RefSeq, Jul 2008],
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功能:
Catalytic activity:L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate.,cofactor:Pyridoxal phosphate.,Disease:Defects in TAT are the cause of tyrosinemia type 2 (TYRO2) [MIM:276600]; also known as Richner-Hanhart syndrome. TYRO2 is an inborn error of metabolism characterized by elevations of tyrosine in the blood and urine, and oculocutaneous manifestations. Typical features include palmoplantar keratosis, painful corneal ulcers, and mental retardation.,pathway:Amino-acid degradation; L-phenylalanine degradation; acetoacetic acid and fumarate from L-phenylalanine: step 2/6.,similarity:Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homodimer.,
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细胞定位:
mitochondrion,cytosol,
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组织表达:
Liver,
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研究领域:
>>Ubiquinone and other terpenoid-quinone biosynthesis ;
>>Cysteine and methionine metabolism ;
>>Tyrosine metabolism ;
>>Phenylalanine metabolism ;
>>Phenylalanine, tyrosine and tryptophan biosynthesis ;
>>Metabolic pathways
>>Cysteine and methionine metabolism ;
>>Tyrosine metabolism ;
>>Phenylalanine metabolism ;
>>Phenylalanine, tyrosine and tryptophan biosynthesis ;
>>Metabolic pathways
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文献引用（{{totalcount}}）
货号: YT4543
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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