SSH3 Rabbit pAb
-YT4428
主要信息
Target
SSH3
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
74kD (Observed)
Conjugate/Modification
Unmodified
货号: YT4428
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
SSH3 Polyclonal Antibody detects endogenous levels of SSH3 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
74kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human SSH3. AA range:357-406
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特异性:
SSH3 Polyclonal Antibody detects endogenous levels of SSH3 protein.
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基因名称:
SSH3
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蛋白名称:
Protein phosphatase Slingshot homolog 3
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别名:
SSH3 ;
SSH3L ;
Protein phosphatase Slingshot homolog 3 ;
SSH-like protein 3 ;
SSH-3L ;
hSSH-3L
SSH3L ;
Protein phosphatase Slingshot homolog 3 ;
SSH-like protein 3 ;
SSH-3L ;
hSSH-3L
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背景:
The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM, Mar 2008],
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功能:
Catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,Catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,Function:Protein phosphatase which may play a role in the regulation of actin filament dynamics. Can dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly.,miscellaneous:Tyrosine phosphatase activity has not been demonstrated for this protein to date.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein-tyrosine phosphatase family.,similarity:Contains 1 tyrosine-protein phosphatase domain.,subunit:Does not bind to, or colocalize with, filamentous actin.,
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细胞定位:
Cytoplasm, cytoskeleton . Nucleus .
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组织表达:
Cerebellum,Epithelium,Ovarian carcinoma,Uterus,
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研究领域:
>>Axon guidance ;
>>Regulation of actin cytoskeleton
>>Regulation of actin cytoskeleton
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文献引用（{{totalcount}}）
货号: YT4428
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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