The antiserum was produced against synthesized peptide derived from human Serpin A5. AA range:260-309

PAI-3 Polyclonal Antibody detects endogenous levels of PAI-3 protein.

SERPINA5

Plasma serine protease inhibitor

SERPINA5 ;
PCI ;
PLANH3 ;
Plasma serine protease inhibitor ;
Acrosomal serine protease inhibitor ;
Plasminogen activator inhibitor 3 ;
PAI-3 ;
PAI3 ;
Protein C inhibitor ;
PCI ;
Serpin A5

The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. [provided by RefSeq, Aug 2012],

Function:Inhibits activated protein C as well as plasminogen activators.,similarity:Belongs to the serpin family.,tissue specificity:Expressed by the liver and secreted in plasma.,

Secreted, extracellular space . Localized on the plasma membrane overlying the acrosomal head of spermatozoa of ependymal spermatozoa and ejaculated sperm. Localized at the equatorial segment of acrosome-reacted spematozoa. Localized in alpha granules in resting platelets and on the external plasma membrane and within the surface-connected cannalicular system in activated platelets.

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