NCoA-5 Rabbit pAb
-YT2997
主要信息
Target
NCoA-5
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
IHC, IF, ELISA
MW
65kD (Observed)
Conjugate/Modification
Unmodified
货号: YT2997
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
NCoA-5 Polyclonal Antibody detects endogenous levels of NCoA-5 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
65kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human NCOA5. AA range:345-394
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特异性:
NCoA-5 Polyclonal Antibody detects endogenous levels of NCoA-5 protein.
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基因名称:
NCOA5
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蛋白名称:
Nuclear receptor coactivator 5
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别名:
NCOA5 ;
KIAA1637 ;
Nuclear receptor coactivator 5 ;
NCoA-5 ;
Coactivator independent of AF-2 ;
CIA
KIAA1637 ;
Nuclear receptor coactivator 5 ;
NCoA-5 ;
Coactivator independent of AF-2 ;
CIA
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背景:
This gene encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Two alternatively spliced transcript variants for this gene have been described. However, the full length nature of one of the variants has not been determined. [provided by RefSeq, Jul 2008],
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功能:
Domain:Contains one Leu-Xaa-Xaa-Leu-Leu (LxxLL) motif that is essential for the association with nuclear receptors.,Function:Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. Involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC/c-myc in response to 17-beta-estradiol (E2).,subunit:Binds HTATIP2/TIP30.,tissue specificity:Widely expressed.,
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细胞定位:
Nucleus.
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组织表达:
Widely expressed.
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文献引用（{{totalcount}}）
货号: YT2997
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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