MLK2 Rabbit pAb
-YT2785
主要信息
Target
MLK2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
IHC, IF, ELISA
MW
104kD (Calculated)
Conjugate/Modification
Unmodified
货号: YT2785
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
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详细信息
推荐稀释比
IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
MLK2 Polyclonal Antibody detects endogenous levels of MLK2 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
104kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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RS0002
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YM3028
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YM3029
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human MAP3K10. AA range:391-440
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特异性:
MLK2 Polyclonal Antibody detects endogenous levels of MLK2 protein.
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基因名称:
MAP3K10
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蛋白名称:
Mitogen-activated protein kinase kinase kinase 10
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别名:
MAP3K10 ;
MLK2 ;
MST ;
Mitogen-activated protein kinase kinase kinase 10 ;
Mixed lineage kinase 2 ;
Protein kinase MST
MLK2 ;
MST ;
Mitogen-activated protein kinase kinase kinase 10 ;
Mixed lineage kinase 2 ;
Protein kinase MST
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背景:
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008],
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功能:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.,Function:Activates the JUN N-terminal pathway.,PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH3 domain.,subunit:Homodimer.,tissue specificity:Expressed in brain and skeletal muscle.,
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细胞定位:
intracellular,cytoplasm,
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组织表达:
Expressed in brain and skeletal muscle.
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研究领域:
>>Huntington disease ;
>>Pathways of neurodegeneration - multiple diseases
>>Pathways of neurodegeneration - multiple diseases
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信号通路
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货号: YT2785
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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