The antiserum was produced against synthesized peptide derived from human MAP4K6. AA range:401-450

MINK1 Polyclonal Antibody detects endogenous levels of MINK1 protein.

MINK1

Misshapen-like kinase 1

MINK1 ;
B55 ;
MAP4K6 ;
MINK ;
YSK2 ;
ZC3 ;
Misshapen-like kinase 1 ;
GCK family kinase MiNK ;
MAPK/ERK kinase kinase kinase 6 ;
MEK kinase kinase 6 ;
MEKKK 6 ;
Misshapen/NIK-related kinase ;
Mitogen-activated protein kinase kinase kinase kinase 6

This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. [provided by RefSeq, Mar 2016],

Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,Function:Serine/threonine kinase that may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in the development of the brain.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 CNH domain.,similarity:Contains 1 protein kinase domain.,tissue specificity:Expressed in the brain, isoform 2 is more abundant than isoform 1.,

Cytoplasm . Cell junction, synapse, postsynaptic density . Cell projection, axon . Cell projection, dendrite .; [Isoform 4]: Golgi apparatus.

Expressed in the brain, isoform 2 is more abundant than isoform 1. Isoform 3 is ubiquitously expressed. Isoform 1 is most abundant in the skeletal muscle. Isoform 4 is ubiquitously expressed with relative high levels in brain, skeletal muscle, pancreas and testis.