ME2 Rabbit pAb
-YT2694
主要信息
Target
ME2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC, IF, ELISA
MW
65kD (Observed)
Conjugate/Modification
Unmodified
货号: YT2694
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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已收藏
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
ME2 Polyclonal Antibody detects endogenous levels of ME2 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
65kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human ME2. AA range:201-250
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特异性:
ME2 Polyclonal Antibody detects endogenous levels of ME2 protein.
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基因名称:
ME2
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蛋白名称:
NAD-dependent malic enzyme mitochondrial
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别名:
ME2 ;
NAD-dependent malic enzyme ;
mitochondrial ;
NAD-ME ;
Malic enzyme 2
NAD-dependent malic enzyme ;
mitochondrial ;
NAD-ME ;
Malic enzyme 2
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背景:
This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene. [provided by RefSeq, Dec 2009],
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功能:
Catalytic activity:(S)-malate + NAD(+) = pyruvate + CO(2) + NADH.,cofactor:Divalent metal cations. Prefers magnesium or manganese.,enzyme regulation:Subject to allosteric activation by fumarate.,miscellaneous:This isoenzyme can also use NADP(+) but is more effective with NAD(+).,similarity:Belongs to the malic enzymes family.,subunit:Homotetramer.,
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细胞定位:
Mitochondrion matrix .
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组织表达:
研究领域:
>>Pyruvate metabolism ;
>>Carbon metabolism
>>Carbon metabolism
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文献引用（{{totalcount}}）
货号: YT2694
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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