LHR Rabbit pAb
-YT2558
主要信息
Target
LHR
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IF, ELISA, IHC
MW
80kD (Observed)
Conjugate/Modification
Unmodified
货号: YT2558
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300; IF 1:200-1:1000; ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
LHR Polyclonal Antibody detects endogenous levels of LHR protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
80kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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RS0002
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YM3028
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GAPDH (PTR2304) Mouse mAb
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human LSHR. AA range:621-670
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特异性:
LHR Polyclonal Antibody detects endogenous levels of LHR protein.
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基因名称:
LHCGR LCGR LGR2 LHRHR
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蛋白名称:
Lutropin-choriogonadotropic hormone receptor
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别名:
LHCGR ;
LCGR ;
LGR2 ;
LHRHR ;
Lutropin-choriogonadotropic hormone receptor ;
LH/CG-R ;
Luteinizing hormone receptor ;
LHR ;
LSH-R
LCGR ;
LGR2 ;
LHRHR ;
Lutropin-choriogonadotropic hormone receptor ;
LH/CG-R ;
Luteinizing hormone receptor ;
LHR ;
LSH-R
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背景:
This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia. [provided by RefSeq, Jul 2008],
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功能:
Alternative products:Additional isoforms seem to exist,Disease:Defects in LHCGR are a cause of familial male precocious puberty (FMPP) [MIM:176410]; also known as testotoxicosis. In FMPP the receptor is constitutively activated.,Disease:Defects in LHCGR are a cause of Leydig cell hypoplasia (LCH) [MIM:152790]. LCH is an autosomal recessive disease characterized by male pseudohermaphroditism. In LCH the testes are small with marked immaturity of the Leydig cells which correlates with undetectable plasma testosterone levels and elevated gonadotropins.,Function:Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.,online information:Glycoprotein-hormone Receptors Information System,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.,similarity:Contains 7 LRR (leucine-rich) repeats.,tissue specificity:Gonadal and thyroid cells.,
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细胞定位:
Cell membrane ; Multi-pass membrane protein .
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组织表达:
研究领域:
>>Calcium signaling pathway ;
>>cAMP signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>Ovarian steroidogenesis ;
>>Prolactin signaling pathway
>>cAMP signaling pathway ;
>>Neuroactive ligand-receptor interaction ;
>>Ovarian steroidogenesis ;
>>Prolactin signaling pathway
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信号通路
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货号: YT2558
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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