GCLM Rabbit pAb
-YT1884
主要信息
Target
GCLM
Host Species
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Applications
WB, IHC, IF, ELISA
MW
31kD (Observed)
Conjugate/Modification
Unmodified
货号: YT1884
规格
价格
货期
数量
200μL
￥3,780.00
一个月
0
100μL
￥2,300.00
一个月
0
40μL
￥960.00
一个月
0
加入购物车
已收藏
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
GCSm-γ Polyclonal Antibody detects endogenous levels of GCSm-γ protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
31kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human GCSm-gamma. AA range:42-91
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特异性:
GCSm-γ Polyclonal Antibody detects endogenous levels of GCSm-γ protein.
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基因名称:
GCLM
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蛋白名称:
Glutamate--cysteine ligase regulatory subunit
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别名:
GCLM ;
GLCLR ;
Glutamate--cysteine ligase regulatory subunit ;
GCS light chain ;
Gamma-ECS regulatory subunit ;
Gamma-glutamylcysteine synthetase regulatory subunit ;
Glutamate--cysteine ligase modifier subunit
GLCLR ;
Glutamate--cysteine ligase regulatory subunit ;
GCS light chain ;
Gamma-ECS regulatory subunit ;
Gamma-glutamylcysteine synthetase regulatory subunit ;
Glutamate--cysteine ligase modifier subunit
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背景:
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015],
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功能:
pathway:Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.,similarity:Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.,subunit:Heterodimer of a catalytic heavy chain and a regulatory light chain.,tissue specificity:In all tissues examined. Highest levels in skeletal muscle.,
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细胞定位:
cytosol,glutamate-cysteine ligase complex,
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研究领域:
>>Cysteine and methionine metabolism ;
>>Glutathione metabolism ;
>>Metabolic pathways ;
>>Biosynthesis of cofactors ;
>>Ferroptosis
>>Glutathione metabolism ;
>>Metabolic pathways ;
>>Biosynthesis of cofactors ;
>>Ferroptosis
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文献引用（{{totalcount}}）
货号: YT1884
规格
价格
货期
数量
200μL
￥3,780.00
一个月
0
100μL
￥2,300.00
一个月
0
40μL
￥960.00
一个月
0
加入购物车
已收藏
收藏
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