FRS3 Rabbit pAb
-YT1793
主要信息
Target
FRS3
Host Species
Rabbit
Reactivity
Human, Monkey
Applications
WB, ELISA
MW
54kD (Observed)
Conjugate/Modification
Unmodified
货号: YT1793
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
FRS3 Polyclonal Antibody detects endogenous levels of FRS3 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
54kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human FRS3. AA range:191-240
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特异性:
FRS3 Polyclonal Antibody detects endogenous levels of FRS3 protein.
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基因名称:
FRS3
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蛋白名称:
Fibroblast growth factor receptor substrate 3
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别名:
FRS3 ;
Fibroblast growth factor receptor substrate 3 ;
FGFR substrate 3 ;
FGFR-signaling adaptor SNT2 ;
Suc1-associated neurotrophic factor target 2 ;
SNT-2
Fibroblast growth factor receptor substrate 3 ;
FGFR substrate 3 ;
FGFR-signaling adaptor SNT2 ;
Suc1-associated neurotrophic factor target 2 ;
SNT-2
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背景:
This gene encodes a substrate for the fibroblast growth factor receptor. The encoded protein is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. The encoded protein down-regulates extracellular regulated kinase 2 through direct binding. [provided by RefSeq, Jul 2013],
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功能:
Function:Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.,PTM:Phosphorylated on tyrosine residues upon stimulation by BFGF or NGFB.,similarity:Contains 1 IRS-type PTB domain.,subunit:Binds NTRK1 (By similarity). Binds FGFR1, NGFR, GRB2, PTPN11 and ERK2.,
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细胞定位:
Membrane; Lipid-anchor.
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组织表达:
Brain,Placenta,
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文献引用（{{totalcount}}）
货号: YT1793
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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