The antiserum was produced against synthesized peptide derived from human EDG3. AA range:115-164

EDG-3 Polyclonal Antibody detects endogenous levels of EDG-3 protein.

S1PR3

Sphingosine 1-phosphate receptor 3

S1PR3 ;
EDG3 ;
Sphingosine 1-phosphate receptor 3 ;
S1P receptor 3 ;
S1P3 ;
Endothelial differentiation G-protein coupled receptor 3 ;
Sphingosine 1-phosphate receptor Edg-3 ;
S1P receptor Edg-3

This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function. [provided by RefSeq, Jul 2008],

Function:Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.,

Cell membrane; Multi-pass membrane protein.

Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver.

>>Sphingolipid signaling pathway ;
>>Neuroactive ligand-receptor interaction