CES2 Rabbit pAb
-YT0874
主要信息
Target
CES2
Host Species
Rabbit
Reactivity
Human
Applications
WB, IHC, IF, ELISA
MW
61kD (Observed)
Conjugate/Modification
Unmodified
货号: YT0874
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
CES2 Polyclonal Antibody detects endogenous levels of CES2 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
61kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from the Internal region of human CES2.
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特异性:
CES2 Polyclonal Antibody detects endogenous levels of CES2 protein.
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基因名称:
CES2
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蛋白名称:
Cocaine esterase
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别名:
CES2 ;
ICE ;
Cocaine esterase ;
Carboxylesterase 2 ;
CE-2 ;
hCE-2 ;
Methylumbelliferyl-acetate deacetylase 2
ICE ;
Cocaine esterase ;
Carboxylesterase 2 ;
CE-2 ;
hCE-2 ;
Methylumbelliferyl-acetate deacetylase 2
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背景:
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010],
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功能:
Catalytic activity:A carboxylic ester + H(2)O = an alcohol + a carboxylate.,Function:Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of 4-methyumbelliferyl acetate, heroin and 6-monoacetylmorphine.,PTM:Glycosylated.,similarity:Belongs to the type-B carboxylesterase/lipase family.,subunit:Monomer.,tissue specificity:Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum.,
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细胞定位:
Endoplasmic reticulum lumen .
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研究领域:
>>Drug metabolism - other enzymes
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文献引用（{{totalcount}}）
货号: YT0874
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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