CD50/ICAM-3 Rabbit pAb
-YT0767
主要信息
Target
CD50
Host Species
Rabbit
Reactivity
Human
Applications
WB, IF, ELISA
MW
42-60kD (Observed)
Conjugate/Modification
Unmodified
货号: YT0767
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
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详细信息
推荐稀释比
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
CD50 Polyclonal Antibody detects endogenous levels of CD50 protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
42-60kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human CD50/ICAM-3. AA range:484-533
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特异性:
CD50 Polyclonal Antibody detects endogenous levels of CD50 protein.
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基因名称:
ICAM3
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蛋白名称:
Intercellular adhesion molecule 3
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别名:
ICAM3 ;
Intercellular adhesion molecule 3 ;
ICAM-3 ;
CDw50 ;
ICAM-R ;
CD antigen CD50
Intercellular adhesion molecule 3 ;
ICAM-3 ;
CDw50 ;
ICAM-R ;
CD antigen CD50
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背景:
The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016],
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功能:
Function:ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2.,online information:ICAM-3,PTM:N-glycosylated; glycans consist of a mixture of tri- and tetra-antennary complex-type chains and high-mannose chains.,PTM:Upon stimulation by a physiologic stimuli becomes rapidly and transiently phosphorylated on serine residues.,similarity:Belongs to the immunoglobulin superfamily. ICAM family.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains.,
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细胞定位:
Membrane; Single-pass type I membrane protein.
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组织表达:
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研究领域:
>>Cell adhesion molecules
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文献引用（{{totalcount}}）
货号: YT0767
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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