ADM Rabbit pAb
-YT0136
主要信息
Target
ADM
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
MW
20kD (Calculated)
Conjugate/Modification
Unmodified
货号: YT0136
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
ADM Polyclonal Antibody detects endogenous levels of ADM protein.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
20kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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RS0002
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human ADM. AA range:51-100
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特异性:
ADM Polyclonal Antibody detects endogenous levels of ADM protein.
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基因名称:
ADM
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蛋白名称:
ADM
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别名:
ADM ;
AM ;
ADM
AM ;
ADM
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背景:
The protein encoded by this gene is a preprohormone which is cleaved to form two biologically active peptides, adrenomedullin and proadrenomedullin N-terminal 20 peptide. Adrenomedullin is a 52 aa peptide with several functions, including vasodilation, regulation of hormone secretion, promotion of angiogenesis, and antimicrobial activity. The antimicrobial activity is antibacterial, as the peptide has been shown to kill E. coli and S. aureus at low concentration. [provided by RefSeq, Aug 2014],
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功能:
Function:AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.,similarity:Belongs to the adrenomedullin family.,tissue specificity:Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues.,
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细胞定位:
Secreted.
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研究领域:
>>Neuroactive ligand-receptor interaction ;
>>Vascular smooth muscle contraction
>>Vascular smooth muscle contraction
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文献引用（{{totalcount}}）
货号: YT0136
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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