Rictor (Phospho Thr1135) Rabbit pAb
-YP1466
主要信息
Target
Rictor
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB, IHC
MW
190kD (Observed)
Conjugate/Modification
Phospho
货号: YP1466
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
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详细信息
推荐稀释比
WB 1:500-2000; IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Human Mouse Rictor (phospho-Thr1135)
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
190kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized phosho peptide around human Rictor (Thr1135)
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特异性:
This antibody detects endogenous levels of Human Mouse Rictor (phospho-Thr1135)
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基因名称:
RICTOR KIAA1999
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蛋白名称:
Rictor (Thr1135)
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别名:
Rapamycin-insensitive companion of mTOR ;
AVO3 homolog ;
hAVO3 ;
AVO3 homolog ;
hAVO3 ;
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背景:
RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008],
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功能:
Function:Plays an essential role in embryonic growth and development (By similarity). Part of the TORC2 complex which plays a critical role in AKT1 'Ser-473' phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.,similarity:Belongs to the pianissimo family.,subunit:Forms part of the target of rapamycin 2 complex (TORC2) comprised of FRAP1, LST8, PROTOR1, RICTOR and MAPKAP1. TORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Binds directly to FRAP1 and PROTOR1 within the TORC2 complex. May interact with PROTOR2.,
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细胞定位:
cytosol,TORC2 complex,
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组织表达:
Amygdala,Brain,Epithelium,Lymph,
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研究领域:
>>mTOR signaling pathway
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货号: YP1466
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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