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FOXM1 (Phospho Ser35) Rabbit pAb

-YP1336

5 4 2
主要信息
Target

FOXM1

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

WB

MW

83kD (Observed)

Conjugate/Modification

Phospho

货号: YP1336
规格
价格
货期
数量
200μL
¥4,680.00
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0

100μL
¥2,800.00
现货

0

50μL
¥1,500.00
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0

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详细信息
推荐稀释比
WB 1:1000-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of Human FoxM1 (phospho-Ser35)
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
83kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized phosho peptide around human FoxM1 (Ser35)
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特异性:
This antibody detects endogenous levels of Human FoxM1 (phospho-Ser35)
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基因名称:
FOXM1 FKHL16 HFH11 MPP2 WIN
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蛋白名称:
Forkhead box protein M1 (Ser35)
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别名:
Forkhead box protein M1 ;
Forkhead-related protein FKHL16 ;
Hepatocyte nuclear factor 3 forkhead homolog 11 ;
HFH-11 ;
HNF-3/fork-head homolog 11 ;
M-phase phosphoprotein 2 ;
MPM-2 reactive phosphoprotein 2 ;
Transcription factor Trident ;
Winged-helix factor from INS-1 cells ;
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数据库链接:
Organism 基因 ID SwissProt
Human 2305; Q08050;
Mouse O08696;
Rat P97691;
背景:
The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011],
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功能:
Alternative products:Isoform 1 and isoform 2 appear to be the only activators of gene transcription. Isoform 3, found in rat, does not seem to exist in human,developmental stage:Embryonic expression pattern: liver, lung, intestine, kidney, urinary tract; adult expression pattern: intestine, colon, testis and thymus.,Domain:Within the protein there is a domain which acts as a transcriptional activator. Insertion of a splicing sequence within it inactivates this transcriptional activity, as it is the case for isoform 4.,Function:Transcriptional activatory factor. May play a role in the control of cell proliferation.,induction:Induced during liver regeneration and oxidative stress.,PTM:Phosphorylated in M (mitotic) phase.,similarity:Contains 1 fork-head DNA-binding domain.,tissue specificity:Expressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells.,
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细胞定位:
Nucleus.
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组织表达:
Expressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Isoform 2 is highly expressed in testis.
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研究领域:
>>Cellular senescence
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货号: YP1336
规格
价格
货期
数量
200μL
¥4,680.00
现货

0

100μL
¥2,800.00
现货

0

50μL
¥1,500.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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