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Vimentin (Phospho Tyr38) Rabbit pAb

-YP1209

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主要信息
Target

Vimentin

Host Species

Rabbit

Reactivity

Human:Y38, Mouse:Y38, Rat:Y38

Applications

WB, ELISA

MW

51kD (Observed)

Conjugate/Modification

Phospho

货号: YP1209
规格
价格
货期
数量
200μL
¥4,680.00
现货

0

100μL
¥2,800.00
现货

0

50μL
¥1,500.00
现货

0

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详细信息
推荐稀释比
WB 1:500-10000; ELISA 1:10000
组成
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
特异性
This antibody detects endogenous levels of Vimentin at Human:Y38;Mouse:Y38;Rat:Y38, It doesn't reacte with total protein.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RTySL
纯化工艺
The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
51kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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ELISA Kits
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抗原&靶点信息
免疫原:
Synthesized phospho-peptide around the phosphorylation site of human Vimentin (Phospho-Tyr38)
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特异性:
This antibody detects endogenous levels of Vimentin at Human:Y38;Mouse:Y38;Rat:Y38, It doesn't reacte with total protein.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RTySL
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基因名称:
VIM
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蛋白名称:
vimentin
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别名:
VIM
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数据库链接:
Organism 基因 ID SwissProt
Human 7431; P08670;
Mouse 22352; P20152;
Rat 81818; P31000;
背景:
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009],
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功能:
Function:Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.,online information:Vimentin entry,PTM:One of the most prominent phosphoproteins in various cells of mesenchymal origin. Phosphorylation is enhanced during cell division, at which time vimentin filaments are significantly reorganized.,sequence Caution:Intron retention.,similarity:Belongs to the intermediate filament family.,subunit:Homopolymer. Interacts with HCV core protein. Interacts with LGSN and SYNM.,tissue specificity:Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.,
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细胞定位:
Cytoplasm . Cytoplasm, cytoskeleton . Nucleus matrix . Cell membrane .
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组织表达:
Highly expressed in fibroblasts, some expression in T- and B-lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.
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研究领域:
>>Epstein-Barr virus infection ;
>>MicroRNAs in cancer
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货号: YP1209
规格
价格
货期
数量
200μL
¥4,680.00
现货

0

100μL
¥2,800.00
现货

0

50μL
¥1,500.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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