eEF2K (Phospho Ser359) Rabbit pAb
-YP1093
主要信息
Target
eEF2K
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
IHC, IF, ELISA
MW
82kD (Calculated)
Conjugate/Modification
Phospho
货号: YP1093
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-eEF2K (S359) Polyclonal Antibody detects endogenous levels of eEF2K protein only when phosphorylated at S359.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GsPRV
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
82kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human eEF2K around the phosphorylation site of Ser359. AA range:336-385
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特异性:
Phospho-eEF2K (S359) Polyclonal Antibody detects endogenous levels of eEF2K protein only when phosphorylated at S359.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GsPRV
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基因名称:
EEF2K
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蛋白名称:
Eukaryotic elongation factor 2 kinase
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别名:
EEF2K ;
Eukaryotic elongation factor 2 kinase ;
eEF-2 kinase ;
eEF-2K ;
Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
Eukaryotic elongation factor 2 kinase ;
eEF-2 kinase ;
eEF-2K ;
Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
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背景:
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008],
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功能:
Catalytic activity:ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate.,enzyme regulation:Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.,Function:Phosphorylates eukaryotic elongation factor-2. Binds calmodulin.,similarity:Belongs to the protein kinase superfamily. Alpha-type protein kinase family.,similarity:Contains 1 alpha-type protein kinase domain.,subunit:Monomer or homodimer .,
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细胞定位:
cytoplasm,cytosol,postsynaptic density,
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组织表达:
研究领域:
>>AMPK signaling pathway ;
>>Oxytocin signaling pathway
>>Oxytocin signaling pathway
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信号通路
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货号: YP1093
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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