The antiserum was produced against synthesized peptide derived from human POU2F1/OCT1 around the phosphorylation site of Ser385. AA range:361-410

Phospho-Oct-1 (S385) Polyclonal Antibody detects endogenous levels of 41183 protein only when phosphorylated at S385.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):RTsIE

POU2F1

POU domain class 2 transcription factor

POU2F1 ;
OCT1 ;
OTF1 ;
POU domain ;
class 2, transcription factor 1 ;
NF-A1 ;
Octamer-binding protein 1 ;
Oct-1 ;
Octamer-binding transcription factor 1 ;
OTF-1 ;
POU2F2 ;
OCT2 ;
OTF2 ;
POU domain, class 2, transcription factor 2 ;
Lymphoid-restricted im

The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010],

Function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.,PTM:Phosphorylated by PRKDC.,similarity:Belongs to the POU transcription factor family. Class-2 subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 POU-specific domain.,subunit:Interacts with NR3C1, AR, PGR and HCFC1.,tissue specificity:Ubiquitous. Isoform 2 is lymphocyte-specific.,

Nucleus.

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