SPAK (Phospho Ser309) Rabbit pAb
-YP0799
主要信息
Target
SPAK
Host Species
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB, IHC, IF, ELISA
MW
60kD (Observed)
Conjugate/Modification
Phospho
货号: YP0799
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-SPAK (S311) Polyclonal Antibody detects endogenous levels of SPAK protein only when phosphorylated at S311.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GKsFR
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
60kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
相关产品
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Primary Antibodies
SPAK (Phospho Ser309) Rabbit pAb
YP0799
预览→
ELISA Kits
Total STK39 Cell-Based Colorimetric ELISA Kit
KA4295C
预览→
抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human STK39 around the phosphorylation site of Ser311. AA range:277-326
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特异性:
Phospho-SPAK (S311) Polyclonal Antibody detects endogenous levels of SPAK protein only when phosphorylated at S311.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):GKsFR
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基因名称:
STK39
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蛋白名称:
STE20/SPS1-related proline-alanine-rich protein kinase
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别名:
STK39 ;
SPAK ;
STE20/SPS1-related proline-alanine-rich protein kinase ;
Ste-20-related kinase ;
DCHT ;
Serine/threonine-protein kinase 39
SPAK ;
STE20/SPS1-related proline-alanine-rich protein kinase ;
Ste-20-related kinase ;
DCHT ;
Serine/threonine-protein kinase 39
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背景:
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq, Jul 2008],
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功能:
Catalytic activity:ATP + a protein = ADP + a phosphoprotein.,Domain:PAPA box (proline-alanine repeats) may target the kinase to a specific subcellular location by facilitating interaction with intracellular proteins such as actin or actin-like proteins.,Function:May act as a mediator of stress-activated signals.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subcellular location:Nucleus when caspase-cleaved.,tissue specificity:Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis.,
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细胞定位:
Cytoplasm . Nucleus . Nucleus when caspase-cleaved. .
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组织表达:
Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis.
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货号: YP0799
规格
价格
货期
数量
200μL
￥4,680.00
现货
0
100μL
￥2,800.00
现货
0
50μL
￥1,500.00
现货
0
加入购物车
已收藏
收藏
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