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SNAI 1 (Phospho Ser246) Rabbit pAb

-YP0568

5 4 2
主要信息
Target

SNAI1

Host Species

Rabbit

Reactivity

Human, Mouse, Monkey

Applications

WB, IHC, IF, ELISA

MW

29kD (Observed)

Conjugate/Modification

Phospho

货号: YP0568
规格
价格
货期
数量
200μL
¥4,680.00
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0

100μL
¥2,800.00
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0

50μL
¥1,500.00
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详细信息
推荐稀释比
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications.
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
Phospho-SNAI 1 (S246) Polyclonal Antibody detects endogenous levels of SNAI 1 protein only when phosphorylated at S246.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):TFsRM
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
29kD
修饰
Phospho
克隆性
Polyclonal
同种型
IgG
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YP0568

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ELISA Kits
Total SNAI 1 Cell-Based Colorimetric ELISA Kit
KA4285C

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ELISA Kits
SNAI 1 (Phospho Ser246) Cell-Based Colorimetric ELISA Kit
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抗原&靶点信息
免疫原:
The antiserum was produced against synthesized peptide derived from human SNAI1 around the phosphorylation site of Ser246. AA range:215-264
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特异性:
Phospho-SNAI 1 (S246) Polyclonal Antibody detects endogenous levels of SNAI 1 protein only when phosphorylated at S246.The name of modified sites may be influenced by many factors, such as species (the modified site was not originally found in human samples) and the change of protein sequence (the previous protein sequence is incomplete, and the protein sequence may be prolonged with the development of protein sequencing technology). When naming, we will use the "numbers" in historical reference to keep the sites consistent with the reports. The antibody binds to the following modification sequence (lowercase letters are modification sites):TFsRM
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基因名称:
SNAI1
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蛋白名称:
Zinc finger protein SNAI1(snail)
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别名:
SNAI1 ;
SNAH ;
Zinc finger protein SNAI1 ;
Protein snail homolog 1 ;
Protein sna
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数据库链接:
Organism 基因 ID SwissProt
Human 6615; O95863;
Mouse 20613; Q02085;
背景:
snail family transcriptional repressor 1(SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008],
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功能:
Function:Seems to be involved in embryonic mesoderm formation. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.,similarity:Belongs to the snail C2H2-type zinc-finger protein family.,similarity:Contains 4 C2H2-type zinc fingers.,tissue specificity:Expressed in a variety of tissues with the highest expression in kidney.,
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细胞定位:
Nucleus . Cytoplasm . Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. .
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组织表达:
Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines.
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研究领域:
>>Adherens junction
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货号: YP0568
规格
价格
货期
数量
200μL
¥4,680.00
现货

0

100μL
¥2,800.00
现货

0

50μL
¥1,500.00
现货

0

加入购物车

已收藏

收藏

定制服务咨询

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