SDCCAG3 Rabbit pAb
-YN6005
主要信息
Target
ENTR1
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
48kD (Calculated)
Conjugate/Modification
Unmodified
货号: YN6005
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of SDCCAG3 at Human, Mouse
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
理论分子量
48kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human SDCCAG3
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特异性:
This antibody detects endogenous levels of SDCCAG3 at Human, Mouse
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基因名称:
SDCCAG3
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蛋白名称:
Serologically defined colon cancer antigen 3 (Antigen NY-CO-3)
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功能:
Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis . Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1 . Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1 . Plays a role in the formation of cilia . Involved in cargo protein localization, such as PKD2, at primary cilia . Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis (By similarity).
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细胞定位:
Cytoplasm . Early endosome . Endosome . Recycling endosome . Midbody . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body . Colocalizes in a WASHC2-dependent manner with the retromer CSC complex at endosomes (PubMed:25278552). During cytokinesis colocalized with PTPN13 at the midbody (PubMed:23108400). Colocalizes with IFT88 and gamma-tubulin at the basal body of primary cilia (PubMed:27767179). Colocalizes with IFT88 and pericentrin at the centrosome (PubMed:27767179). .
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组织表达:
Expressed in the colon (at protein level).
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文献引用（{{totalcount}}）
货号: YN6005
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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