Synthesized peptide derived from human MAT2B AA range: 23-73

This antibody detects endogenous levels of MAT2B at Human/Mouse/Rat

MAT2B TGR MSTP045 Nbla02999 UNQ2435/PRO4995

MAT2B

The protein encoded by this gene belongs to the methionine adenosyltransferase (MAT) family. MAT catalyzes the biosynthesis of S-adenosylmethionine from methionine and ATP. This protein is the regulatory beta subunit of MAT. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012],

Function:Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition.,miscellaneous:Its expression in hepatoma cell lines may lead to increase DNA synthesis and thereby participate to cell proliferation.,pathway:Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.,similarity:Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.,subunit:Heterotetramer composed of 2 catalytic alpha subunits (alpha and alpha') (MAT2A) and 1 copy of beta subunit (MAT2B).,tissue specificity:Widely expressed.,

intracellular,nucleus,mitochondrion,cytosol,methionine adenosyltransferase complex,extracellular exosome,

Widely expressed.

>>Cysteine and methionine metabolism ;
>>Metabolic pathways ;
>>Biosynthesis of amino acids ;
>>Biosynthesis of cofactors