PP6R2 Rabbit pAb
-YN3315
主要信息
Target
PP6R2
Host Species
Rabbit
Reactivity
Human, Mouse
Applications
WB
MW
105kD (Observed)
Conjugate/Modification
Unmodified
货号: YN3315
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
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详细信息
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
特异性
This antibody detects endogenous levels of PP6R2 at Human/Mouse
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
实测条带
105kD
修饰
Unmodified
克隆性
Polyclonal
同种型
IgG
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抗原&靶点信息
免疫原:
Synthesized peptide derived from human PP6R2 AA range: 59-109
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特异性:
This antibody detects endogenous levels of PP6R2 at Human/Mouse
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基因名称:
PPP6R2 KIAA0685 PP6R2 SAPS2
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蛋白名称:
PP6R2
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别名:
Serine/threonine-protein phosphatase 6 regulatory subunit 2 ;
SAPS domain family member 2 ;
SAPS domain family member 2 ;
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背景:
Protein phosphatase regulatory subunits, such as SAPS2, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS2 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010],
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功能:
Function:Regulatory subunit of protein phospatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha.,similarity:Belongs to the SAPS family.,subunit:Protein phospatase 6 (PP6) holoenzyme is proposed to be a heterotrimeric complex formed by the catalytic subunit, a SAPS domain-containing subunit (PP6R) and an ankyrin repeat-domain containing regulatory subunit (ARS). Interacts with PPP6C and NFKBIE. Interacts with ANKRD28.,tissue specificity:Ubiquitously expressed with strongest expression in the testis followed by liver, heart, kidney, brain and placenta.,
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细胞定位:
Cytoplasm .
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组织表达:
Ubiquitously expressed with strongest expression in the testis followed by liver, heart, kidney, brain and placenta.
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文献引用（{{totalcount}}）
货号: YN3315
规格
价格
货期
数量
200μL
￥3,780.00
现货
0
100μL
￥2,300.00
现货
0
40μL
￥960.00
现货
0
加入购物车
已收藏
收藏
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